发明名称 |
Method for preparing 3-methylindole derivatives through hydrogenation |
摘要 |
There is disclosed a preparation method of 3-methylindole derivatives by reducing the aldehyde moiety in indole-3-carboxaldehyde derivatives in the presence of the copper or copper oxide-based hydrogenation catalyst. This process is performed in solvent under the condition of 50-300 DEG C and 50-1,000 psig in the presence of a solvent with a hydrogen atmosphere. The method is advantageous in the economic aspects because of the employment of a relatively inexpensive hydrogenation catalyst and the easy regeneration thereof. Further, this process is environmentally safe because the intended addition of the sulfur components is not required therefor. |
申请公布号 |
EP1325911(A1) |
申请公布日期 |
2003.07.09 |
申请号 |
EP20030290021 |
申请日期 |
2003.01.06 |
申请人 |
SK CORPORATION |
发明人 |
KWAK, BYONG-SUNG;KIM, TAE-YUN;KIM, JIN-WOONG;LEE, SANG-II |
分类号 |
C07B61/00;C07D209/08 |
主分类号 |
C07B61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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