发明名称 PHARMACEUTICAL PREPARATION USING ALZHEIMER AMYLOID POLYPEPTIDE AND TREATING METHOD
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a pharmaceutical preparation containing an A4i protease and an analogue of the protease, capable of used for treating diseases relating to a Kunitz-type basic protease inhibitor. <P>SOLUTION: This preparation comprises a pharmaceutically acceptable composition used for inhibiting inflammations and contains a pharmaceutical acceptable carrier, the protein expressed by the sequence of formula (1), and the analogue of the protein given by substituting an amino acid which comprises arginine and exists at the 13 position in a sequence with another neutral hydrophobic amino acid. <P>COPYRIGHT: (C)2003,JPO</p>
申请公布号 JP2003192613(A) 申请公布日期 2003.07.09
申请号 JP20020310315 申请日期 2002.10.24
申请人 SCIOS INC 发明人 CORDELL BARBARA;SCHILLING JAMES W;KATSUNUMA NOBUHIKO
分类号 C12N15/09;A61K38/00;A61K38/55;A61K51/08;A61P7/02;A61P7/04;A61P17/02;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07K14/005;C07K14/47;C07K14/81;C07K16/18;C07K16/38;C07K16/40;C07K19/00;C12N1/21;C12N5/00;C12N5/10;C12N9/99;C12N15/71;C12N15/863;C12P21/00;C12Q1/68;C12R1/19;C12R1/91;G01N33/68;(IPC1-7):A61K38/55 主分类号 C12N15/09
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