发明名称 |
Antibacterial aqueous ophthalmic formulations containing ofloxacin and use of chitosan for solubilizing ofloxacin suspended in an aqueous media |
摘要 |
The aqueous ophthalmic formulation for the treatment and prevention of infections contains ofloxacin as active ingredient and a chitosan having a weight average molecular weight of 500,000-5,000,000 Daltons and a deacetylation degree of 30-90% as solubilizing agent of ofloxacin. Chitosan having a deacetylation degree of 30-90% may be also used for solubilizing ofloxacin suspended in an aqueous media having a substantially neutral pH in any other applications.
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申请公布号 |
US6589999(B2) |
申请公布日期 |
2003.07.08 |
申请号 |
US20010859908 |
申请日期 |
2001.05.17 |
申请人 |
LABORATOIRE MEDIDOM S.A. |
发明人 |
GURNY ROBERT;FELT OLIVIA MIREILLE |
分类号 |
A61K9/00;A61K47/36;(IPC1-7):A61K47/00 |
主分类号 |
A61K9/00 |
代理机构 |
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