发明名称 Methods for therapeutic use of brain derived neurotrophic factor in the entorhinal cortex
摘要 A protocol for use of growth factors to stimulate neuronal cell growth and activity in trkB receptor containing cortical tissues, including the entorhinal and hippocampal cortices. The method introduces exogenous growth factor, such as BDNF, NT-4/5 and NT-3, into the EC. The method is useful in therapy of defective, diseased and damaged neurons in the mammalian brain, of particular usefulness for treatment of neurodegenerative conditions such as Alzheimer's disease or for normal aging.
申请公布号 US2003124095(A1) 申请公布日期 2003.07.03
申请号 US20010039078 申请日期 2001.12.31
申请人 REGENTS OF THE UNIVERSITY OF CALIFORNIA 发明人 TUSZYNSKI MARK H.
分类号 A61K38/22;A61K38/18;A61P25/00;A61P25/28;(IPC1-7):A61K48/00 主分类号 A61K38/22
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