发明名称 |
Nucleic acid ligand complexes |
摘要 |
This invention discloses a method for preparing a therapeutic or diagnostic complex comprised of a nucleic acid ligand and a lipophilic compound or non-immunogenic, high molecular weight compound by identifying a nucleic acid ligand by SELEX methodology and associating the nucleic acid ligand with a lipophilic compound or a non-immunogenic, high molecular weight compound. The invention further discloses complexes comprising one or more nucleic acid ligands in association with a lipophilic compound or non-immunogenic, high molecular weight compound.
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申请公布号 |
US2003125263(A1) |
申请公布日期 |
2003.07.03 |
申请号 |
US20020261159 |
申请日期 |
2002.09.30 |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
GOLD LARRY;SCHMIDT PAUL G.;JANJIC NEBOJSA |
分类号 |
A61K9/127;C07B61/00;C07H19/06;C07H19/10;C07H21/00;C07K14/00;C12N9/12;C12N15/10;C12N15/115;C12Q1/37;C12Q1/68;C12Q1/70;F02B75/02;G01N33/531;G01N33/532;G01N33/535;G01N33/569;G01N33/68;G01N33/76;(IPC1-7):A61K48/00;C07J1/00;C07H21/04;C12N15/85 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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