发明名称 |
Antisense modulation of toll-like receptor 4 expression |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of Toll-like receptor 4. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Toll-like receptor 4. Methods of using these compounds for modulation of Toll-like receptor 4 expression and for treatment of diseases associated with expression of Toll-like receptor 4 are provided.
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申请公布号 |
US2003125272(A1) |
申请公布日期 |
2003.07.03 |
申请号 |
US20010001863 |
申请日期 |
2001.11.19 |
申请人 |
KARRAS JAMES G.;KOLLER ERICH |
发明人 |
KARRAS JAMES G.;KOLLER ERICH |
分类号 |
A61K38/00;C12N15/113;(IPC1-7):A61K48/00;C12Q1/68;C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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地址 |
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