发明名称 Modification of virus tropism and host range by viral genome shuffling
摘要 The invention relates to a method and compositions for modifying a phenotype of a virus, such as viral tropism and host range, by iterative sequence recombination of variant viruses and selection of improved variants.
申请公布号 US2003124708(A1) 申请公布日期 2003.07.03
申请号 US20020310741 申请日期 2002.12.04
申请人 MAXYGEN, INC. 发明人 STEMMER WILLEM P.C.;PATTEN PHILLIP;SOONG NAY WEI
分类号 A61K39/00;C07K14/15;C07K14/16;C07K14/18;C12N7/01;C12N15/10;(IPC1-7):C12N7/01;C12N15/867;C12N7/00;C07H21/04;C12N5/06;C12N5/12;C12N15/86 主分类号 A61K39/00
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