发明名称 METHOD FOR MAKING A TABLET COMPRISING A MORPHINE TYPE ANALGESIC AND RESULTING TABLET
摘要 The invention concerns a method for making a tablet comprising at least a morphine derivative type analgesic, for fighting against secondary effects of said analgesic on the intestinal mucosa. Said method is characterized in that it consists in combining said analgesic with a low density excipient and in directly compressing the mixture so as to obtain a floating homogeneous tablet with prolonged gastric residence time. The invention also concerns the resulting tablet.
申请公布号 WO03053417(A2) 申请公布日期 2003.07.03
申请号 WO2002FR04488 申请日期 2002.12.20
申请人 ELLIPSE PHARMACEUTICALS;LACAZE-SAINT-JEAN, CATHERINE;CUART, SYLVIE;TERRASSIN, LAURENT 发明人 LACAZE-SAINT-JEAN, CATHERINE;CUART, SYLVIE;TERRASSIN, LAURENT
分类号 A61K9/00;A61K9/20;A61K9/22;A61K31/135;A61K31/137;A61K31/222;A61K31/395;A61K31/451;A61K31/485;A61P25/04;(IPC1-7):A61K9/22 主分类号 A61K9/00
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