发明名称 |
Cyclic ether vitamin D3 compounds, 1alpha(OH) 3-epi- vitamin D3 compounds and uses thereof |
摘要 |
Novel cyclic ether vitamin D3 compounds having a cyclic ether side chain are disclosed. These compounds were first identified as metabolites of 3-epi vitamin D3 produced via a tissue-specific metabolic pathway which catalyzes the formation of a cyclic ether structure. Also disclosed are 1alpha(OH) 3-epi vitamin D3 compounds, which are produced via the epimerization of a 3-beta-hydroxyl group of 1alpha(OH) vitamin D3 precursor in vivo. The vitamin D3 compounds of the present invention can be used as substitutes for natural and synthetic vitamin D3 compounds.
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申请公布号 |
US2003125309(A1) |
申请公布日期 |
2003.07.03 |
申请号 |
US20020188320 |
申请日期 |
2002.07.01 |
申请人 |
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发明人 |
REDDY SATAYANARAYANA G. |
分类号 |
A61K31/045;A61K31/351;A61P3/00;A61P3/02;A61P3/14;A61P5/18;A61P17/00;A61P19/08;A61P19/10;A61P43/00;C07C401/00;C07D303/14;C07D307/33;C07D309/04;C07D309/06;(IPC1-7):A61K31/59;C0739/10 |
主分类号 |
A61K31/045 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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