发明名称 TETRAHYDROBENZFLUORENE DERIVATIVES
摘要 <p>A compound having formula (I), wherein the O-(CH2)n-N(R1,R2) substituent on the phenyl ring can be in meta or para position; n is 2-4, Re and 'Re are OH, optionally independently etherified or esterified; R1 and R2 are independently (1C-4C)alkyl, (2C-4C)alkenyl, hydroxy(2C-4C)alkyl, (1C-3C)alkoxy(2C-4C)alkyl, aryl or aryl(1C-2C)alkyl; or R1 and R2 together with the nitrogen form an aromatic or non-aromatic heterocyclic ring structure, optionally mono- or poly-substituted with (1C-4C)alkyl, (2C-4C)alkenyl, hydroxy(1C-2C)alkyl, (1C-2C)alkoxy(1C-3C)alkyl or aryl. These compounds can be used for estrogen receptor β selective medical treatments.</p>
申请公布号 WO2003053994(A1) 申请公布日期 2003.07.03
申请号 EP2002014283 申请日期 2002.12.16
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