摘要 |
A costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity. |
申请人 |
THE JOHNS HOPKINS UNIVERSITY;PARDOLL, DREW, M.;TSUCHIYA, HARUO;GORSKI, KEVIN, S.;TSENG, SU-YI |
发明人 |
PARDOLL, DREW, M.;TSUCHIYA, HARUO;GORSKI, KEVIN, S.;TSENG, SU-YI |