| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a new method for producing an intermediate for a biologically active substance having high activities for inhibiting dipeptidylpeptidase IV. <P>SOLUTION: This method for producing a compound represented by general formula (2) [wherein, n is an integer of 0-3; and Y is a protective group of an amino group] comprises, for example, reacting a silylation agent with a compound represented by general formula (1) [wherein, n and Y are each the same as the above], and further reacting the product with P (=O) T3 (T is a halogen atom) and ammonia in order. <P>COPYRIGHT: (C)2003,JPO</p> |
