| 发明名称 |
Compositions and methods for stabilizing biological molecules upon lyophilization |
| 摘要 |
The present invention is directed to compositions and methods for the preparation of biological molecules, in particular MenC-CRM 197. Biological molecules dissolved in dissolution buffers comprising at least one amorphous excipient and an amorphous buffer exhibit reduced aggregation and proteolytic breakdown.
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| 申请公布号 |
US2003124139(A1) |
申请公布日期 |
2003.07.03 |
| 申请号 |
US20020148559 |
申请日期 |
2002.11.20 |
| 申请人 |
ESIKOVA IRINA;WOLFE SIDNEY;THOMSON JAMES;HORA MANINDER |
发明人 |
ESIKOVA IRINA;WOLFE SIDNEY;THOMSON JAMES;HORA MANINDER |
| 分类号 |
A61K9/00;A61K9/19;A61K39/095;A61K47/18;A61K47/26;(IPC1-7):A61K39/00 |
主分类号 |
A61K9/00 |
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