发明名称 INHIBITION OF TRISTETRAPROLINE FOR PROTECTION OF THE HEART FROM CARDIAC INJURIES
摘要 The present invention relates to compounds suitable for the treatment of conditions which may be improved, at least in part, by increasing TNF alpha production. The invention further relates to assays for the identification of an individual at increased risk for or suffering from such conditions and to methods of screening compounds for their ability to enhance TNF alpha biosysthesis.
申请公布号 WO03054541(A2) 申请公布日期 2003.07.03
申请号 WO2002EP13545 申请日期 2002.11.30
申请人 MERCK PATENT GMBH;KLUXEN, FRANZ-WERNER;HENTSCH, BERND;EHRING, THOMAS;BRAENDLE, MARIAN;HOHEISEL, JOERG, DIETRICH;FROHME, MARCUS;ZUBAKOV, DIMITRI 发明人 KLUXEN, FRANZ-WERNER;HENTSCH, BERND;EHRING, THOMAS;BRAENDLE, MARIAN;HOHEISEL, JOERG, DIETRICH;FROHME, MARCUS;ZUBAKOV, DIMITRI
分类号 G01N33/53;A61K31/7088;A61K39/395;A61K48/00;A61P9/04;A61P9/10;A61P43/00;C07K16/18;C12N15/09;C12Q1/68;G01N33/566;G01N33/68 主分类号 G01N33/53
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