发明名称 |
USE OF KETOCONAZOLE AND RELATED SUBSTANCES IN MEDICAMENTS FOR TREATMENT OF TYPE II DIABETES |
摘要 |
<p>An inhibitor (A) of cortisol synthesis is used: (a) to treat type II diabetes mellitus; and (b) to counteract other risk factors that are part of the metabolic syndrome (also known as the deadly quartet, syndrome X or insulin resistance syndrome). (A) is ketoconazole (I; already well known as an antimycotic) or its derivs. with comparable activity. Men treated with (A) may need to receive testosterone, since (A) also inhibits prodn. of this hormone.</p> |
申请公布号 |
EP0779810(B1) |
申请公布日期 |
2003.07.02 |
申请号 |
EP19940927881 |
申请日期 |
1994.08.09 |
申请人 |
METABOLIC SYNDROME I GOETEBORG AB |
发明人 |
MARIN, PER |
分类号 |
C07D405/06;A61J3/02;A61K31/495;A61K31/496;A61K31/50;A61K31/565;A61K45/00;A61M15/00;A61P3/06;A61P3/08;A61P3/10;A61P9/12;B65B1/08;B65B1/30;C07J1/00;(IPC1-7):A61K31/495 |
主分类号 |
C07D405/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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