| 摘要 |
Antibodies, antibody fragments or single chain antibodies that specifically bind to human and mouse orthologs of the Zsig-9 secreted polypeptide are provided, the antibodies are preferably monoclonal. Also provided are methods of using the antibodies of the invention as well as in-vitro methods of diagnosing cancer in human tissues or body fluids utilising the antibodies of the invention or antisense nucleic acid sequences that specifically bind to Zsig-9 polynucleotide sequences. The invention is of particular use in diagnosing cancers such as brain tumour, liver tumour, lung tumour, esophageal tumour, stomach tumour, colon tumour, rectal tumour, thyroid tumour, or lymphoma tumour.
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