发明名称 Method and kit for confirming in vitro the diagnosis of the coeliac disease
摘要 In order to diagnose the coeliac disease antiendomysial antibodies are detected through immunofluorescence techniques in culture media in which bioptic fragments of the human enteral mucosa are kept alive. The cultures of the enteral mucosa take place by dipping the bioptic fragment into nutrient liquids with or without the presence of low concentrations of peptic-tryptic digest of gliadin. The peptide fragment of gliadin containing a definite aminoacid sequence capable of production of antiendomysial antibodies to a greater extent than the PT digest, even in very little concentration, is also identified.
申请公布号 EP0821238(B1) 申请公布日期 2003.07.02
申请号 EP19970830381 申请日期 1997.07.23
申请人 PICARELLI, ANTONIO 发明人 PICARELLI, ANTONIO
分类号 C07K14/415;G01N33/68 主分类号 C07K14/415
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