发明名称 |
Mono-allelic mutation analysis for identifying germline mutations |
摘要 |
A diagnostic strategy for detection of inherited diseases caused by germline mutations is based on somatic cell hybridization. Each allele of a human gene involved in the inherited disease is isolated in a somatic cell hybrid. The products of the isolated human allele are then observed in the absence of the other allele of the human.
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申请公布号 |
USRE38168(E1) |
申请公布日期 |
2003.07.01 |
申请号 |
US20000569326 |
申请日期 |
2000.05.11 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
VOGELSTEIN BERT;KINZLER KENNETH W.;PAPADOPOULOS NICKOLAS |
分类号 |
C12Q1/68;G01N33/50;G01N33/68;(IPC1-7):C12Q1/68;C12P19/34;C07M21/02 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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