发明名称 |
Chemical sensors and method of use |
摘要 |
Chemical sensor compositions and methods for quantifying analytes are described. The chemical sensors include analyte-binding moieties and reporter moieties covalently attached to a framework including two trityl groups connected by a linear spacer such as ethyne or butadiyne. The sensors chelate an analyte across the acetylene axis of the molecule to stabilize the molecule in an eclipsed rotamer conformation. This conformation causes the sensors to emit a measurable signal. Also disclosed are methods of making the chemical sensors, methods of using the chemical sensors, and kits for quantifying analytes using the chemical
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申请公布号 |
US6586256(B1) |
申请公布日期 |
2003.07.01 |
申请号 |
US20000562202 |
申请日期 |
2000.05.02 |
申请人 |
THE PENN STATE RESEARCH FOUNDATION |
发明人 |
GLASS TIMOTHY E.;RAKER JOSEPH;MORAN RICARDO |
分类号 |
G01N21/64;G01N21/78;(IPC1-7):G01N21/64 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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