| 发明名称 |
Humanized antibodies that bind specifically to verotoxin II (VT2) and/or VT2 variant and the B subunits thereof |
| 摘要 |
Described are humanized antibodies that specifically bind to, and preferably, neutralize, verotoxin II (VT2). The antibodies are useful for treating patients suffering from, or at risk of suffering, toxic effects of verotoxin.
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| 申请公布号 |
NZ508119(A) |
申请公布日期 |
2003.06.30 |
| 申请号 |
NZ19990508119 |
申请日期 |
1999.05.19 |
| 申请人 |
TEIJIN LIMITED;PROTEIN DESIGN LABS, INC |
发明人 |
CO, MAN SUNG;VASQUES, MAXIMILIANO;MATSUMOTO, YOH-ICHI;IMAIZUMI, ATSUCHI;KIMURA, TSUYOSHI;TAKEDO, TAE |
| 分类号 |
C12N15/02;A61K31/04;A61K38/00;A61K39/02;A61K39/108;A61K39/395;A61K39/40;A61P31/04;A61P43/00;C07K16/12;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/02;C12N5/07;C12N5/10;C12P21/04;C12P21/08;(IPC1-7):A61K39/02;C12N5/06 |
主分类号 |
C12N15/02 |
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