发明名称 Form VI of 5,6-dichloro-2-(isopropylamino)-1-(beta-L-ribofuranosyl)-1H-benzimidazole
摘要 The crystalline form VI of 5,6-dichloro-2-(isopropylamino)-1b-L-ribofuranosyl-1H-benzimidazole is characterized by an X-ray powder diffraction pattern expressed in terms of 2 theta angles and obtained with a diffractometer equipped with a diffracted beam graphite monochromator using copper Ka X-radiation with the X-ray powder diffraction pattern comprising 2 theta angle at 8.53 ± 0.05 degrees. The compound 5,6-dichloro-2-(isopropylamino)-1b-L-ribofuranosyl-1H-benzimidazole has the formula (I). A crystalline form of 5,6-dichloro-2-(isopropylamino)-1b-L-ribofuranosyl-1H-benzimidazole is characterized by an X-ray powder diffraction pattern expressed in terms of 2 theta angles and obtained with a diffractometer equipped with a diffracted beam graphite monochromator using copper Ka X-radiation with the X-ray powder diffraction pattern comprising 2 theta angles at five or more positions selected from the group consisting of 8.53 ± 0.05, 10.47 ± 0.05, 13.51 ± 0.05, 14.95 ± 0.05, 15.98 ± 0.05, 17.23 ± 0.05, 21.41 ± 0.05, 21.83 ± 0.05, 22.35 ± 0.05, 23.07 ± 0.05, and 27.49 ± 0.05 degrees. The compounds are useful for treating viral infections.
申请公布号 NZ507012(A) 申请公布日期 2003.06.30
申请号 NZ19990507012 申请日期 1999.04.01
申请人 GLAXO GROUP LIMITED 发明人 CARTER, BARRY HOWARD;HODGSON, ANNE;HUANG, LIAN-FENG
分类号 A61K31/70;A61K31/7042;A61K31/7052;A61K31/7056;A61P31/12;C07H19/052;(IPC1-7):C07H19/052;A61K31/705 主分类号 A61K31/70
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