发明名称 ANALGESIC REGIMEN
摘要 1. A regimen for the treatment of analgesia which comprises administering a pharmaceutical composition containing tramadol as the active ingredient which comprises: about 10-50 mg of tramadol on days 1-3; about 20-100 mg of tramadol on days 4-6; about 30-150 mg of tramadol on days 7-9; and about 40-400 mg of tramadol on days 10-28 and thereafter. 2. A regimen for the treatment of analgesia according to claim 1 which comprises administering a pharmaceutical composition containing tramadol as the active ingredient which comprises: about 10-50 mg of tramadol on days 1-3; about 20-100 mg of tramadol on days 4-6; about 30-150 mg of tramadol on days 7-9; and about 40-200 mg of tramadol on days 10-28 and thereafter. 3. A regimen for the treatment of analgesia according to claim 1 which comprises administering a pharmaceutical composition containing tramadol as the active ingredient which comprises: 25 mg of tramadol on days 1-3; 50 mg of tramadol on days 4-6; 75 mg of tramadol on days 7-9; 100 mg of tramadol on days 10-12; 150 mg of tramadol on days 13-15; and 200 mg of tramadol on days 16-28 and thereafter. 4. A regimen for the treatment of analgesia according to claim 1 which comprises administering a pharmaceutical composition containing tramadol as the active ingredient which comprises: 50 mg of tramadol on days 1-3; 100 mg of tramadol on days 4-6; 150 mg of tramadol on days 7-9; and 200 mg of tramadol on day 10 and thereafter. 5. A regimen for the treatment of analgesia according to claim 1 which comprises administering a pharmaceutical composition containing tramadol as the active ingredient which comprises: 25 mg of tramadol on days 1-3; 50 mg of tramadol on days 4-6; 75 mg of tramadol on days 7-9; 100 mg of tramadol on days 10-12; 150 mg of tramadol on days 13-15; and 200 mg of tramadol on day 16 and thereafter. 6. A regimen for the treatment of analgesia according to claim 1 which comprises administering a pharmaceutical composition containing tramadol as the active ingredient which comprises: 25 mg of tramadol q. d. on days 1-3, 25 of mg of tramadol b. i. d. on days 4-6, 25 mg of tramadol t. i. d. on days 7-9, 25 mg of tramadol q. i. d. on days 10-12, and 50 mg of tramadol t. i. d. on days 13-28. 7. The method of claim 1 wherein tramadol is administered in the form of tramadol hydrochloride.
申请公布号 EA003557(B1) 申请公布日期 2003.06.26
申请号 EA20010000501 申请日期 1999.10.12
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC. 发明人 KAMIN, MARC;OLSON, WILLIAM
分类号 A61K31/135;A61P19/02;A61P25/04;(IPC1-7):A61K31/135 主分类号 A61K31/135
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