发明名称 MEDICINAL COMPOSITIONS ADHERING TO STOMACH/DUODENUM
摘要 1. Pharmaceutical gastric and/or duodenal adhesive dosage form characterized in that the form is obtained by coating a composition, which comprises a medicament acting at the stomach and/or duodenum and water insoluble cellulose polymer (I), polymer (II), having adhesive capacity onto the surface of the mucosa of a digestive tract under acid conditions and separates from the mucosa of the digestive tract in neutral or alkaline conditions, wherein said polymer is obtained from acrylic acid and/or methacrylic acid and carbon acid ester. 2. Pharmaceutical dosage form according to claim 1, characterized in that the polymer (II) is so-polymer of methacrylic acid and methacrylate. 3. Pharmaceutical dosage form according to claim 1, characterized in that the polymer (I) is ethylcellulose. 4. Pharmaceutical dosage form according to claim 2, characterized in that the polymer (I) is ethylcellulose. 5. Pharmaceutical dosage form according to claim 1, characterized in that the polymer (II) is conditions is soluble in a solution of at least pH 4.
申请公布号 EA003512(B1) 申请公布日期 2003.06.26
申请号 EA20000000973 申请日期 1999.03.17
申请人 KOWA CO., LTD. 发明人 INAGI, TOSHIO;SHIRAI, HIROYUKI;YAMAGUCHI, NORIKAZU;NISHINO, TAKESHI
分类号 A61K9/00;A61K9/50;(IPC1-7):A61K9/30 主分类号 A61K9/00
代理机构 代理人
主权项
地址