发明名称 HYDROXYPHENYL-PYRAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
摘要 The present invention provides a method for treating diseases caused by and/or associated with an altered protein kinase activity which comprises administering to a mammal in need thereof and effective amount of o-hydroxy phenyl-pyrazol-3-yl derivatives optionally substituted of formula (I). The invention also provides some new compounds, a library comprising at least two of them, a process for their preparation and the pharmaceutical compositions containing them, which are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, viral infections, autoimmune diseases and neurodegenerative disorders.
申请公布号 WO03051358(A1) 申请公布日期 2003.06.26
申请号 WO2002EP14087 申请日期 2002.12.11
申请人 PHARMACIA ITALIA SPA;CASUSCELLI, FRANCESCO;D'ALESSIO, ROBERTO;FELDER, EDUARD;VULPETTI, ANNA 发明人 CASUSCELLI, FRANCESCO;D'ALESSIO, ROBERTO;FELDER, EDUARD;VULPETTI, ANNA
分类号 A61K31/415;A61K31/4155;A61K31/422;A61K31/4439;A61K31/455;A61K31/498;A61K45/00;A61P1/04;A61P9/10;A61P11/00;A61P13/08;A61P13/12;A61P17/06;A61P19/02;A61P25/00;A61P25/28;A61P31/12;A61P35/00;A61P35/02;A61P35/04;A61P37/06;A61P43/00;C07D231/12;C07D401/04;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/12;(IPC1-7):A61K31/415 主分类号 A61K31/415
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