发明名称 |
HYDROXYPHENYL-PYRAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM |
摘要 |
The present invention provides a method for treating diseases caused by and/or associated with an altered protein kinase activity which comprises administering to a mammal in need thereof and effective amount of o-hydroxy phenyl-pyrazol-3-yl derivatives optionally substituted of formula (I). The invention also provides some new compounds, a library comprising at least two of them, a process for their preparation and the pharmaceutical compositions containing them, which are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, viral infections, autoimmune diseases and neurodegenerative disorders.
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申请公布号 |
WO03051358(A1) |
申请公布日期 |
2003.06.26 |
申请号 |
WO2002EP14087 |
申请日期 |
2002.12.11 |
申请人 |
PHARMACIA ITALIA SPA;CASUSCELLI, FRANCESCO;D'ALESSIO, ROBERTO;FELDER, EDUARD;VULPETTI, ANNA |
发明人 |
CASUSCELLI, FRANCESCO;D'ALESSIO, ROBERTO;FELDER, EDUARD;VULPETTI, ANNA |
分类号 |
A61K31/415;A61K31/4155;A61K31/422;A61K31/4439;A61K31/455;A61K31/498;A61K45/00;A61P1/04;A61P9/10;A61P11/00;A61P13/08;A61P13/12;A61P17/06;A61P19/02;A61P25/00;A61P25/28;A61P31/12;A61P35/00;A61P35/02;A61P35/04;A61P37/06;A61P43/00;C07D231/12;C07D401/04;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/12;(IPC1-7):A61K31/415 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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