| 发明名称 |
USE OF UROKINASE RECEPTOR ANTAGONISTS TO MODULATE ISCHEMIAREPERFUSION INJURY |
| 摘要 |
The invention relates to a method of treatment and/or modulation of ischemia-reperfusion injury. In particular, the invention shows a novel, negative role for the urokinase receptor in the pathogenesis of myocardial ischemia. Consequently, the use of selective inhibitors of u-PAR are of benefit for the treatment of patients suffering from ischemic heart disease.
|
| 申请公布号 |
WO03051347(A1) |
申请公布日期 |
2003.06.26 |
| 申请号 |
WO2002EP14478 |
申请日期 |
2002.12.18 |
| 申请人 |
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW;D. COLLEN RESEARCH FOUNDATION;COLLEN, DESIRE;CARMELIET, PETER;VAN AKEN, HUGO;THEILMEIER, GREGOR |
发明人 |
COLLEN, DESIRE;CARMELIET, PETER;VAN AKEN, HUGO;THEILMEIER, GREGOR |
| 分类号 |
A61K31/00;A61K31/19;A61K31/33;A61K31/343;A61K31/352;A61K31/38;A61K31/40;A61K31/405;A61K31/445;A61K31/496;A61K31/555;A61K38/02;A61K38/49;A61P9/00;(IPC1-7):A61K31/00;A61K35/80;A61K38/03;A61K38/08;A61K38/55 |
主分类号 |
A61K31/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
