| 发明名称 |
Ligands to enhance cellular uptake of biomolecules |
| 摘要 |
The present invention relates to the design and synthesis of homogeneous A-L-P constructs, which contain a hepatic ligand to direct an oligomer or "payload" to a hepatocyte intracellularly via a receptor-mediated, ligand-directed pathway.
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| 申请公布号 |
US2003119724(A1) |
申请公布日期 |
2003.06.26 |
| 申请号 |
US20010888164 |
申请日期 |
2001.06.22 |
| 申请人 |
TS`O PAUL O.P.;DUFF ROBERT;ZHOU YUANZHONG;DEAMOND SCOTT;ROBY CLINTON |
发明人 |
TS`O PAUL O.P.;DUFF ROBERT;ZHOU YUANZHONG;DEAMOND SCOTT;ROBY CLINTON |
| 分类号 |
C12N15/09;A61K31/7088;A61K47/48;A61P1/16;A61P31/12;C07H15/18;C07H21/00;C12N15/11;(IPC1-7):A61K48/00;C07K16/46 |
主分类号 |
C12N15/09 |
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