发明名称 |
Treatment of hyperproliferative diseases |
摘要 |
We describe methods and compositions for treating a patient suffering from a hyperproliferative disorder or photoageing. Our methods involve blocking the activity of a retinol binding protein receptor (RBPr) in cells of the patient, and/or administering to the patient an antagonist of a retinol binding protein receptor (RBPr) and/or lowering the endogenous level of retinoic acid (RA) in cells of said patient.
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申请公布号 |
US2003119715(A1) |
申请公布日期 |
2003.06.26 |
申请号 |
US20020085239 |
申请日期 |
2002.02.27 |
申请人 |
WARD SIMON;BAVIK CLAES;CORK MICHAEL;TAZI-AAHNINI RACHID |
发明人 |
WARD SIMON;BAVIK CLAES;CORK MICHAEL;TAZI-AAHNINI RACHID |
分类号 |
G01N33/50;A61K31/10;A61K31/11;A61K31/145;A61K31/285;A61K31/415;A61K31/56;A61K31/575;A61K31/7088;A61K31/7105;A61K31/711;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K48/00;A61P1/16;A61P3/02;A61P3/06;A61P5/16;A61P9/00;A61P9/10;A61P15/08;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P17/10;A61P17/12;A61P17/14;A61P17/16;A61P19/08;A61P19/10;A61P25/18;A61P25/24;A61P31/12;A61P31/18;A61P31/20;A61P31/22;A61P35/00;A61P37/06;A61P39/06;A61P43/00;C07D231/12;C07J53/00;C07K16/28;C12Q1/02;C12Q1/32;G01N33/15;G01N33/566;(IPC1-7):A61K31/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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