发明名称 DERIVATIVES OF ISOINDIGO, INDIGO AND INDIRUBIN AND USE IN TREATING CANCER
摘要 A compound called NATURA, which is derivative of Isoindigo is useful in aiding the general health of a patient and specifically is beneficial in preventing or treating cancer. This compound and other related Isoindigo, Indigo and Indirubin derivatives are designed such that the bioactivity or bioavailability of the compound is increased. Methods of synthesizing these derivatives is also taught. In addition, pharmaceutical compositions that include a therapeutically effective amount of at least one of these derivatives and a pharmaceutically acceptable carrier. A method for the use of these pharmaceutical compositions and compounds is taught, wherein a therapeutically effective amount is administered to an animal having solid tumor cancer. The pharmaceutical composition or compound can be re-administered to the animal until a desired treatment or result is accomplished.
申请公布号 WO03051900(A1) 申请公布日期 2003.06.26
申请号 WO2002US39866 申请日期 2002.12.13
申请人 NATROGEN THERAPEUTICS, INC.;WANG, LONGGUI;LIU, XIAOMEI;CHEN, RUIHUAN 发明人 WANG, LONGGUI;LIU, XIAOMEI;CHEN, RUIHUAN
分类号 C07H17/02;A61K31/404;A61K31/7056;A61K45/06;A61P35/00;C07D209/34;C07H19/02;C07H19/23;(IPC1-7):C07H19/02 主分类号 C07H17/02
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