发明名称 |
PYRAZINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
The present invention relates to compound of formula (I) and pharmaceutically acceptable salts, solvates and crystalline forms thereof, in which R¿1< represents cyclohexyl, 1-piperidinyl or phenyl; R¿2? represents H, chloro, bromo, methyl or methoxy; and when R¿3? represents H, R¿4? represents H or chloro; and when R¿3? represents chloro, R¿4? represents H or chloro; to processes for preparing such compounds, to their use in the treatment of obesity, psychiatric and neurological disorders particularly obesity, to methods for their therapeutic use and to pharmaceutical compositions containing them.
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申请公布号 |
WO03051850(A1) |
申请公布日期 |
2003.06.26 |
申请号 |
WO2002GB05736 |
申请日期 |
2002.12.18 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;WILSTERMAN, JOHAN, MICHAEL;BERGGREN, ANNA, INGRID, KRISTINA |
发明人 |
WILSTERMAN, JOHAN, MICHAEL;BERGGREN, ANNA, INGRID, KRISTINA |
分类号 |
A61P25/00;C07D241/24;(IPC1-7):C07D241/24;A61K31/496 |
主分类号 |
A61P25/00 |
代理机构 |
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