KLCS AS MODIFIERS OF THE P53 PATHWAY AND METHODS OF USE
摘要
Human KLC genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of KLC are provided.
申请公布号
WO03052066(A2)
申请公布日期
2003.06.26
申请号
WO2002US39633
申请日期
2002.12.12
申请人
EXELIXIS, INC.;COSTA, MICHAEL, A.;HUNG, TAK;PARRY, DIANE;MAXWELL, MARK, E.;LACKNER, MARK
发明人
COSTA, MICHAEL, A.;HUNG, TAK;PARRY, DIANE;MAXWELL, MARK, E.;LACKNER, MARK
