发明名称 SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR)
摘要 The present invention provides the S enantiomer of a compound of formula (I); wherein R1 represents 2,4-difluorophenyl or cyclohexyl as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them.
申请公布号 CA2469302(A1) 申请公布日期 2003.06.26
申请号 CA20022469302 申请日期 2002.12.18
申请人 ASTRAZENECA AB 发明人 ALSTERMARK LINDSTEDT, EVA-LOTTE;OLSSON, ANNA CHRISTINA;LI, LANNA
分类号 A61K45/00;A61K31/16;A61K31/192;A61K31/195;A61K31/40;A61K31/505;A61K31/554;A61K45/06;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P43/00;C07C69/734;C07C69/736;C07C231/12;C07C235/20;C07D235/20;(IPC1-7):C07C235/20 主分类号 A61K45/00
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