发明名称 |
Gene useful for diagnosis and treatment of aplasia of corpus callosum and aspermatogensis and use thereof |
摘要 |
Aplasia of the corpus callosum or aspermatogenesis is diagnosed by investigating existence or expression of the BT-IgSF gene with use of a primer for PCR or probe for hybridization comprising a DNA coding for a novel cell adhesion molecule (BT-IgSF) defined in the following (A) or (B) or a partial sequence thereof: (A) a protein comprising the amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2; (B) a protein comprising an amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2 including substitution, deletion, insertion or addition of one or several amino acids and having a function as a cell adhesion molecule. <IMAGE>
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申请公布号 |
EP1321475(A1) |
申请公布日期 |
2003.06.25 |
申请号 |
EP20020258645 |
申请日期 |
2002.12.16 |
申请人 |
MORINAGA MILK INDUSTRY CO., LTD. |
发明人 |
SUZU, SHINYA;HAGESHITA, HIROAKI;NOMAGUCHI, KOUJI;YAMADA, MUNEO;HAYASAWA, HIROTOSHI |
分类号 |
C12N15/09;A61K38/00;A61K48/00;A61P15/08;A61P43/00;C07K14/47;C07K14/705;C12N15/12;(IPC1-7):C07K14/47;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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