| 发明名称 |
Phosphonic acid derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B) |
| 摘要 |
The invention encompasses the novel class of compounds represented by formula I which are inhibitors of the PTP-1B enzyme.The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, and diabetes-related diseases.
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| 申请公布号 |
US6583126(B2) |
申请公布日期 |
2003.06.24 |
| 申请号 |
US20000745222 |
申请日期 |
2000.12.21 |
| 申请人 |
MERCK EROSST CANADA & CO. |
发明人 |
LEBLANC YVES;DUFRESNE CLAUDE;JOHN SCHEIGETZ;LAU CHEUK KUN;LI CHUN SING;ROY PATRICK;BOYD MICHAEL;WANG ZHAOYIN |
| 分类号 |
A61K45/00;A61K31/662;A61K31/663;A61K31/675;A61K45/06;A61P1/04;A61P1/18;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P25/00;A61P35/00;A61P43/00;C07F9/38;C07F9/40;C07F9/58;C07F9/6518;C07F9/653;(IPC1-7):C07F9/38 |
主分类号 |
A61K45/00 |
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