| 摘要 |
The present invention relates to an alpha-melanocyte stimulating hormone (alpha-MSH) analogue, labeled with an amino acid-type paramagnetic spin probe, for example, Toac, or 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid, and methods for the synthesis thereof. The preferred analogue of the invention, acetyl-Toac0-alpha-MSH (abbreviated as EPM-2) is the first such analogue that maintains entirely the natural alpha-MSH activity.
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