发明名称 |
Aza- indolyl derivatives for treating obesity |
摘要 |
Novel compounds of formula (I):wherein X1, X2, X3 and X4, n, R1, R2 and R3 are defined in the specification, and pharmaceutically acceptable salts and prodrugs of the compounds of formula (I) have therapeutic uses. These compounds are useful for the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes insipidus, and sleep apnea. They are particularly useful for the treatment of obesity.
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申请公布号 |
US6583134(B2) |
申请公布日期 |
2003.06.24 |
申请号 |
US20010794491 |
申请日期 |
2001.02.27 |
申请人 |
HOFFMAN-LA ROCHE INC.;VERNALIS RESEARCH LIMITED |
发明人 |
BENTLEY JONATHAN MARK;HEBEISEN PAUL;TAYLOR SVEN |
分类号 |
A61K31/337;A61K31/437;A61K31/44;A61K45/00;A61P1/00;A61P1/14;A61P3/04;A61P7/02;A61P9/10;A61P11/00;A61P13/00;A61P13/02;A61P15/00;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P29/00;C07D471/14;C07D487/14;(IPC1-7):A61K31/55;C07D223/14;C07D487/00;C07D491/00;C07D515/00 |
主分类号 |
A61K31/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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