| 摘要 |
The present invention relates to a novel tumor suppressor gene, SSeCKS. The SSeCKS gene product is a substrate of protien kinase C and acts as a mitogenic regulator and as an inhibitor of the transformed phenotype. In various embodiments, the present invention relates to the SSeCKS gene and protein and in particular, to rat and human SSeCKS gene and protein. Furthermore, the present invention provides for the use of such genes and proteins in diagnostic and therapeutic methods.
|
