发明名称 |
C3 binding polypeptide of Streptococcus agalactiae group b Streptococcus |
摘要 |
This invention relates to the identification of a human complement C3 binding polypeptide and the nucleic acid which encodes the polypeptide from Streptococcus agalactiae. The polypeptide binds C3 and may be implicated in S. agalactiae adhesion and/or virulence. The polypeptide is conserved in mass in a variety of streptococcal isolates and is recognized by antibodies produced by humans exposed to or colonized with Group B Streptococcus.
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申请公布号 |
US6582950(B1) |
申请公布日期 |
2003.06.24 |
申请号 |
US20000610199 |
申请日期 |
2000.07.01 |
申请人 |
REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
SMITH BEVERLY L.;FERRIERI PATRICIA |
分类号 |
A61K38/00;A61K39/00;C07K14/315;C12N15/31;(IPC1-7):C12N1/20;C12N15/00;C12N5/00;C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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