发明名称 |
HIGHLY TRITIUM-LABELED TAFCINE AND METHOD OF DETERMINATION OF TAFCINE IN BIOLOGICAL SAMPLES |
摘要 |
FIELD: analytical chemistry. SUBSTANCE: invention relates to novel compound tritium-labeled tafcine and to method of determination of tafcine in biological samples. Method involves addition to sample highly tritium- labeled tafcine, extraction, conversion of tafcine and its labeled analogue to their benzoin or ortho-phthalic derivatives in prepared extract followed by their analysis by HPLC method with fluorescent detector. Proposed tafcine is a highly labeled compound and method ensures to determine microamounts of tafcine. EFFECT: improved preparing method, enhanced sensitivity of method. 2 cl, 2 tbl, 7 ex
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申请公布号 |
RU2206556(C1) |
申请公布日期 |
2003.06.20 |
申请号 |
RU20010133613 |
申请日期 |
2001.12.14 |
申请人 |
INSTITUT MOLEKULJARNOJ GENETIKI RAN |
发明人 |
SHEVCHENKO V.P.;MJASOEDOV N.F.;NAGAEV I.JU. |
分类号 |
C07B59/00;A61K51/08;C07K5/10;(IPC1-7):C07B59/00 |
主分类号 |
C07B59/00 |
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