发明名称 |
NOVEL MONOFUNCTIONAL POLYETHYLENE GLYCOL ALDEHYDES |
摘要 |
Novel monofunctional polyethylene glycol aldehyde for pegylating therapeutically active proteins to produce pegylated protein conjugates which retain a substantial portion of their therapeutic activity and are less immunogenic than the protein from which the conjugate is derived and a new synthesis for preparing such aldehydes. |
申请公布号 |
WO03049699(A2) |
申请公布日期 |
2003.06.19 |
申请号 |
WO2002US39434 |
申请日期 |
2002.12.09 |
申请人 |
SUN BIO, INC. |
发明人 |
ROSEN, PERRY;NHO, KWANG |
分类号 |
A61K47/48;C08G65/324;C08G65/329;C08G65/331;C08G65/333 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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