发明名称 |
METHOD AND APPARATUS FOR MAINTENANCE AND EXPANSION OF HEMOPOIETIC STEM CELLS AND/OR PROGENITOR CELLS. |
摘要 |
<p>A method of expanding/maintaining undifferentiated hemopoietic stem cells or progenitor cells by obtaining undifferentiated hemopoietic stem cells or progenitor cells; and either seeding the undifferentiated hemopoietic stem cells or progenitor cells into a stationary phase plug-flow bioreactor in which a three-dimensional stromal cell culture has been pre-established on a substrate in the form of a sheet, the substrate including a non-woven fibrous matrix forming a physiologically acceptable three-dimensional network of fibers, thereby expanding/maintaining undifferentiated hemopoietic stem cells or progenitor cells, or culturing the undifferentiated hemopoietic stem cells or progenitor cells in conditioned medium obtained from such a reactor.</p> |
申请公布号 |
MXPA01007820(A) |
申请公布日期 |
2003.06.19 |
申请号 |
MX2001PA07820 |
申请日期 |
2000.02.04 |
申请人 |
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. |
发明人 |
MERCHAV, SHOSHANA |
分类号 |
C12M3/00;A61F2/00;A61K35/12;A61K35/14;A61P7/00;A61P43/00;C12M3/04;C12N5/00;C12N5/02;C12N5/078;C12N11/08;C12R1/91 |
主分类号 |
C12M3/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|