| 发明名称 |
SUBSTITUTED HYDRAZONES AS INHIBITORS OF CYCLOOXYGENASE-2 |
| 摘要 |
Compounds useful as inhibitors of cyclooxygenase-2 activity have the formulae I or Ia as defined herein. In addition, Figure 2 compares the growth inhibitory activity fo the Example 4 compound 4-bromobenzaldehyde-4- sulfamylphenylhydrazone and celecoxib against the human colo-rectal tumor cell line HT29.
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| 申请公布号 |
CA2469709(A1) |
申请公布日期 |
2003.06.19 |
| 申请号 |
CA20022469709 |
申请日期 |
2002.12.10 |
| 申请人 |
TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
REDDY, M.V. RAMANA;REEDY, E. PREMKUMAR |
| 分类号 |
C07D333/22;A61K31/18;A61K31/341;A61K31/381;A61K31/40;A61K31/4045;A61K31/44;A61K31/63;A61P9/00;A61P9/10;A61P25/28;A61P29/00;A61P43/00;C07C303/40;C07C311/37;C07C311/39;C07C311/49;C07D209/14;C07D307/52;G02B6/12;G02B6/124;G02B6/125;G02B6/28;G02B6/34;G02B6/35;H04Q11/00;(IPC1-7):C07C311/39 |
主分类号 |
C07D333/22 |
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