发明名称 |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes |
摘要 |
This invention discloses a method for preparing a complex comprised of a VEGF Nucleic Acid Ligand and a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound by identifying a VEGF Nucleic Acid Ligand by SELEX methodology and associating the VEGF Nucleic Acid Ligand with a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound. The invention further discloses Complexes comprising one or more VEGF Nucleic Acid Ligands in association with a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound. The invention further includes a Lipid construct comprising a VEGF Nucleic Acid Ligand or Complex and methods for making the same.
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申请公布号 |
US2003114404(A1) |
申请公布日期 |
2003.06.19 |
申请号 |
US20020205009 |
申请日期 |
2002.07.25 |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
JANJIC NEBOJSA;GOLD LARRY;SCHMIDT PAUL;VARGEESE CHANDRA;WILLIS MICHAEL |
分类号 |
A61K31/70;A61K38/00;A61K47/48;C07H21/00;C07K14/52;C12N15/115;C12N15/88;C12Q1/68;(IPC1-7):A61K48/00;C07H21/04;C12P19/34 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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