| 摘要 |
<p>The invention provides compositions and uses thereof for the protection of white matter of the central nervous system. Specifically, it is directed to the use of IGF-I, its analogs and mimetics, and the use of IGF-I, its analogs and mimetics in combination with interferons including beta 1 and consensus interferons, to stimulate glial cells such as mature astrocytes to promote remyelination to treat neuronal disease and injury, such as result from, for example, hypoxia, ischemia, trauma, degenerative and demyelinating diseases.</p> |
