| 摘要 |
<p>A cover slip (22) for forming a chamber (34) of the type for use with a hybridization reaction or similar molecular search. The cover slip has a surface (36) and two substantially parallel, opposed edges (30, 32) bounding the surface. A spacer has a pair of spacer segments (26, 28), and each spacer segment extends along substantially a full length of a different one of the opposed edges, thereby forming a chamber between the space segments, the cover slip and a substrate (24). The chamber receives a specimen (42) when the cover slip is placed on the substrate with the spacer sandwiched therebetween. The cover slip has a thickness providing a beam stiffness permitting the cover slip to maintain a substantially constant distance between the surface and the substrate when a liquid is introduced between the cover slip and the substrate. In another eombidment, the spacer extends along the perimeter of the cover slip and has discontinuities forming two channels (70) across the perimeter for introducing the liquid therethrough. Thespacer determines a distance between the cover slip and the substrate; and the extending along most of the perimeter of the cover slip, the spacer substantially reduces evaporation of the liquid..</p> |
