COMPOSITIONS FOR ORAL GENE THERAPY AND METHODS OF USING SAME
摘要
The present invention provides nanoparticle compositions comprising a cationic biopolymer and at least one biologically active substance, pharmaceutical compositions comprising such nanoparticles and methods for the oral administration of biologically active molecules which are susceptible to degradation in the gastro-intestinal tract using manoparticle. The present invention further provides compositions and methods for the oral administration of gene therapy.
申请公布号
WO03028657(A3)
申请公布日期
2003.06.19
申请号
WO2002US31500
申请日期
2002.10.03
申请人
THE JOHNS HOPKINS UNIVERSITY;LEONG, KAM, W.;OKOLI, GRACE;HORTELANO, GONZALO