THE USE OF OSTEOGENIC GROWTH PEPTIDE IN THE ENHANCEMENT OF HAEMOPOIESIS

摘要

The osteogenic growth peptide (OGP) is a kind of polypeptide that has 14 amino acid residues and exists in the animal and human body. According to the present invention OGP has not only the function in the promotion of ossification but the proliferation of haemopoiesis cells as well. The present invention discloses the use of osteogenic growth peptide in the preparation of the pharmaceutical composition for enhancing the proliferation of haemopoietic cells such as granulocytes. It also provides a method for using the OGP in promoting the development of granulocyte progenitor cell in vitro. OGP is different from the granulocyte or granulocyte monocyte colony stimulating factor in that it does not have the function of stimulating leukemia cell such as human TF-1.