| 发明名称 |
GUANIDINIUM TRANSPORT REAGENTS AND CONJUGATES |
| 摘要 |
Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurali ty of guanidinium moieties that are either contiguous or spaced along a backbon e, but are sufficiently removed from the backbone via tethers, to allow their interaction with a cell or tissue surface, leading to uptake of the therapeutic agent.
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| 申请公布号 |
CA2469336(A1) |
申请公布日期 |
2003.06.19 |
| 申请号 |
CA20022469336 |
申请日期 |
2002.12.11 |
| 申请人 |
CELLGATE, INC.;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
PATTABIRAMAN, KANAKA;PELKEY, ERIN T.;ROTHBARD, JONATHAN B.;WENDER, PAUL A.;JESSOP, THEODORE C. |
| 分类号 |
A61K31/395;A61K31/4188;A61K47/48;A61P29/00;A61P31/04;A61P31/10;A61P35/00;A61P43/00;(IPC1-7):A61K47/48 |
主分类号 |
A61K31/395 |
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