发明名称 Carrier peptide and method for delivery of molecules into cells
摘要 Disclosed is a carrier peptide and a conjugate comprising a carrier peptide and a target molecule and a method for delivery of the target molecule into a cell. The carrier peptide contains from 10-15 amino acids, having a core sequence of 3-5 hydrophobic amino acids flanked by flanking amino acid sequences. The core sequence comprises residues selected from proline and leucine such that there is at least one each of proline and leucine and is symmetrical about an amino acid or a bond. Also disclosed is a method for delivery of a target molecule into a cell and a method for measuring a cellular process.
申请公布号 US2003113819(A1) 申请公布日期 2003.06.19
申请号 US20020148936 申请日期 2002.08.26
申请人 HORTON JEFFREY K;SMITH JOHN A;TEEAR MICHELLE L;KENDALL JONATHAN M;MICHAEL NIGEL P 发明人 HORTON JEFFREY K;SMITH JOHN A;TEEAR MICHELLE L;KENDALL JONATHAN M;MICHAEL NIGEL P
分类号 A61K47/48;A61K49/00;C07K7/08;(IPC1-7):G01N33/574;C07K7/06 主分类号 A61K47/48
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