发明名称 |
High efficiency tissue specific compound delivery system using streptavidin-protein a fusion protein |
摘要 |
The present invention relates to methods and compositions that can be employed to introduce toxins and nucleic acids into the cytoplasm or nucleus of a eukaryotic cell, particularly a cell of a higher vertebrate. The invention particularly concerns the use of a fusion protein of streptavidin and protein A sequences to form a non-covalent complex of a toxin or nucleic acid and an antibody.
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申请公布号 |
US2003113337(A1) |
申请公布日期 |
2003.06.19 |
申请号 |
US20020289921 |
申请日期 |
2002.11.06 |
申请人 |
NEW YORK UNIVERSITY |
发明人 |
MERUELO DANIEL;OHNO KOUICHI;LEVIN BRANDI A. |
分类号 |
C12N15/02;A61K38/00;A61K39/395;A61K47/48;A61K48/00;C07K16/18;C07K16/28;C07K19/00;C12P21/08;(IPC1-7):A61K39/395;C07K16/46 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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