发明名称 FUSION PROTEIN FROM ANTIBODY CYTOKINE-CYTOKINE INHIBITOR (SELECTOKINE) FOR USE AS TARGET-SPECIFIC PRODRUG
摘要 The present invention relates to a polypeptide having preferably antitumoral and/or immunomodulating cytokine properties, which can be activated by processing in vivo comprising a central region with specific biological activity. At its C-terminus said region has a region with a processing unit and an inhibitor domain, while at the N-terminus of the central region, there is a region that selectively recognizes a macromolecule on a cell surface or a component of the extracellular matrix.
申请公布号 KR20030048041(A) 申请公布日期 2003.06.18
申请号 KR20037003738 申请日期 2003.03.14
申请人 发明人
分类号 C07K19/00;C12N15/09;A61K38/00;A61K47/48;A61K48/00;A61P35/00;C07K14/525;C07K14/715;C07K16/18;C07K16/40;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02 主分类号 C07K19/00
代理机构 代理人
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